Name: Quinine#130-95-0
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Quinine#130-95-0

Quinine#130-95-0
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Chemical Name：Quinine
CAS No.:130-95-0
Molecular Formula：C20H24N2O2
Sample: Available
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Quinine#130-95-0

Quinine(130-95-0), an alkaloid derived from the bark of the cinchona tree, is a blood schizontocidal agent that is more toxic than chloroquine. Quinine is used to treat malaria caused by Plasmodium falciparum. Plasmodium falciparum is a parasite that gets into the red blood cells in the body and causes malaria. Quinine works by killing the parasite or preventing it from growing. This medicine may be used alone or given together with one or more medicines for malaria.

Quinine Chemical Properties

Melting point	173-175 °C(lit.)
alpha	-172 º (c=1, EtOH)
Boiling point	462.75°C (rough estimate)
density	1.1294 (rough estimate)
bulk density	110-140kg/m3
vapor pressure	0Pa at 25℃
refractive index	1.6250 (estimate)
Fp	>110°C (>230°F)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	H2O: soluble
form	Crystalline Powder
pka	8.52(at 25℃)
color	White
PH Range	Blue I uorescence (3.0) to weak violet I uorescence (5.0);Weak violet I uorescence (9.5) to nonI uorescence (10.0)
PH	9.0 (0.5g/l, H2O, 20℃)
Odor Type	odorless
Optical Rotation	[α]25/D 165°, c = 2 in ethanol
Water Solubility	slightly soluble
Sensitive	Light Sensitive
Hydrolytic Sensitivity	2: reacts with aqueous acid
Merck	14,8061
BRN	91867
Major Application	Bird repellents, sunscreen, antimalarial agent, antiviral agent, antitumor agent, drug-coated coronaryagent, antiparasitic agent, treatment of epilepsy, skeletal muscle spasm, drug-coated coronary stent system
LogP	3.17 at 25℃
CAS DataBase Reference	130-95-0(CAS DataBase Reference)
NIST Chemistry Reference	Quinine(130-95-0)
EPA Substance Registry System	Quinine (130-95-0)

Product Usage

In addition to its use as an antimalarial agent, quinine medications are used to treat leg cramps, muscle cramps associated with kidney failure, hemorrhoids, heart palpitations, and as an analgesic. At higher concentrations it is toxic and causes a condition known as cinchonism. Conditions associated with cinchonism include dizziness, hearing loss, visual impairment, nausea, and vomiting.

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